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Type-I interferon response affects an inoculation dose-independent mortality in mice following Japanese encephalitis virus infection

BACKGROUND: The laboratory mouse model is commonly employed to study the pathogenesis of encephalitic flaviviruses such as Japanese encephalitis virus (JEV). However, it is known that some strains of these viruses do not elicit a typical mortality dose response curve from this organism after periphe...

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Detalles Bibliográficos
Autores principales: Aoki, Kotaro, Shimada, Satoshi, Simantini, Dash Sima, Tun, Mya Myat Ngwe, Buerano, Corazon C, Morita, Kouichi, Hayasaka, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074870/
https://www.ncbi.nlm.nih.gov/pubmed/24903089
http://dx.doi.org/10.1186/1743-422X-11-105