Development of Dual Inhibitors against Alzheimer's Disease Using Fragment-Based QSAR and Molecular Docking

Alzheimer's (AD) is the leading cause of dementia among elderly people. Considering the complex heterogeneous etiology of AD, there is an urgent need to develop multitargeted drugs for its suppression. β-amyloid cleavage enzyme (BACE-1) and acetylcholinesterase (AChE), being important for AD pr...

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Detalles Bibliográficos
Autores principales: Goyal, Manisha, Dhanjal, Jaspreet Kaur, Goyal, Sukriti, Tyagi, Chetna, Hamid, Rabia, Grover, Abhinav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075005/
https://www.ncbi.nlm.nih.gov/pubmed/25019089
http://dx.doi.org/10.1155/2014/979606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075005/
https://www.ncbi.nlm.nih.gov/pubmed/25019089
http://dx.doi.org/10.1155/2014/979606

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