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Osthole Attenuates Doxorubicin-Induced Apoptosis in PC12 Cells through Inhibition of Mitochondrial Dysfunction and ROS Production

Doxorubicin (DOX) is a potent, broad-spectrum chemotherapeutic drug used for treatment of several types of cancers. Despite its effectiveness, it has a wide range of toxic side effects, many of which most likely result from its inherent prooxidant activity. It has been reported that DOX has toxic ef...

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Detalles Bibliográficos
Autores principales: Shokoohinia, Yalda, Hosseinzadeh, Leila, Moieni-Arya, Maryam, Mostafaie, Ali, Mohammadi-Motlagh, Hamid-Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075090/
https://www.ncbi.nlm.nih.gov/pubmed/25013759
http://dx.doi.org/10.1155/2014/156848