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The association of angiotensin-converting enzyme with biomarkers for Alzheimer’s disease

INTRODUCTION: Lower angiotensin-converting enzyme (ACE) activity could increase the risk of Alzheimer’s disease (AD) as ACE functions to degrade amyloid-β (Aβ). Therefore, we investigated whether ACE protein and activity levels in cerebrospinal fluid (CSF) and serum were associated with CSF Aβ, tota...

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Detalles Bibliográficos
Autores principales: Jochemsen, Hadassa M, Teunissen, Charlotte E, Ashby, Emma L, van der Flier, Wiesje M, Jones, Ruth E, Geerlings, Mirjam I, Scheltens, Philip, Kehoe, Patrick G, Muller, Majon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075229/
https://www.ncbi.nlm.nih.gov/pubmed/24987467
http://dx.doi.org/10.1186/alzrt257