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Autophagy Promotes Primary Ciliogenesis by Removing OFD1 from Centriolar Satellites

The primary cilium is a microtubule-based organelle that functions in sensory and signaling pathways. Defects in ciliogenesis can lead to a group of genetic syndromes known as ciliopathies(1–3). However, the regulatory mechanisms of primary ciliogenesis in normal and cancer cells are incompletely un...

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Detalles Bibliográficos
Autores principales: Tang, Zaiming, Lin, Mary Grace, Stowe, Timothy R., Chen, She, Zhu, Muyuan, Stearns, Tim, Franco, Brunella, Zhong, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075283/
https://www.ncbi.nlm.nih.gov/pubmed/24089205
http://dx.doi.org/10.1038/nature12606