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Compounds used to produce cloned animals are genotoxic and mutagenic in mammalian assays in vitro and in vivo
The compounds 6-dimethylaminopurine and cycloheximide promote the successful production of cloned mammals and have been used in the development of embryos produced by somatic cell nuclear transfer. This study investigated the effects of 6-dimethylaminopurine and cycloheximide in vitro, using the thi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075292/ https://www.ncbi.nlm.nih.gov/pubmed/24714812 http://dx.doi.org/10.1590/1414-431X20143301 |