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Insulin Receptor Expression in Clear Cell Renal Cell Carcinoma and Its Relation to Prognosis
PURPOSE: Both insulin and insulin-like growth factor (IGF)-1 signaling are key regulators of energy metabolism, cellular growth, proliferation, and survival. The IGF-1 receptor (IGF-1R) is overexpressed in most types of human cancers including renal cell carcinoma (RCC) with poor prognosis. Insulin...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075388/ https://www.ncbi.nlm.nih.gov/pubmed/24954312 http://dx.doi.org/10.3349/ymj.2014.55.4.861 |