Insulin Receptor Expression in Clear Cell Renal Cell Carcinoma and Its Relation to Prognosis

PURPOSE: Both insulin and insulin-like growth factor (IGF)-1 signaling are key regulators of energy metabolism, cellular growth, proliferation, and survival. The IGF-1 receptor (IGF-1R) is overexpressed in most types of human cancers including renal cell carcinoma (RCC) with poor prognosis. Insulin...

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Detalles Bibliográficos
Autores principales: Lkhagvadorj, Sayamaa, Oh, Sung Soo, Lee, Mi-Ra, Jung, Jae Hung, Chung, Hyun Chul, Cha, Seung-Kuy, Eom, Minseob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075388/
https://www.ncbi.nlm.nih.gov/pubmed/24954312
http://dx.doi.org/10.3349/ymj.2014.55.4.861

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