A Novel Synthetic Compound 3-Amino-3-(4-Fluoro-Phenyl)-1H-Quinoline-2,4-Dione (KR22332) Exerts a Radioprotective Effect via the Inhibition of Mitochondrial Dysfunction and Generation of Reactive Oxygen Species

PURPOSE: Acute side effects of radiation such as oral mucositis are observed in most patients. Although several potential radioprotective agents have been proposed, no effective agent has yet been identified. In this study, we investigated the effectiveness of synthetic compound 3-amino-3-(4-fluoro-...

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Detalles Bibliográficos
Autores principales: Baek, Seung Jae, Chang, Jae Won, Park, Keun Hyung, Yang, Garp Yeol, Hwang, Hye Sook, Koh, Yoon Woo, Jung, Young-Sik, Kim, Chul-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075391/
https://www.ncbi.nlm.nih.gov/pubmed/24954315
http://dx.doi.org/10.3349/ymj.2014.55.4.886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075391/
https://www.ncbi.nlm.nih.gov/pubmed/24954315
http://dx.doi.org/10.3349/ymj.2014.55.4.886

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