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Use of the computer-retargeted group II intron RmInt1 of Sinorhizobium meliloti for gene targeting

Gene-targeting vectors derived from mobile group II introns capable of forming a ribonucleoprotein (RNP) complex containing excised intron lariat RNA and an intron-encoded protein (IEP) with reverse transcriptase (RT), maturase, and endonuclease (En) activities have been described. RmInt1 is an effi...

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Detalles Bibliográficos
Autores principales: M García-Rodríguez, Fernando, Hernández-Gutiérrez, Teresa, Díaz-Prado, Vanessa, Toro, Nicolás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075523/
https://www.ncbi.nlm.nih.gov/pubmed/24646865
http://dx.doi.org/10.4161/rna.28373