A recombinant RNA bacteriophage system to identify functionally important nucleotides in a self-cleaving ribozyme

BACKGROUND: RNA bacteriophages like Qbeta and MS2 are well known for their high mutation rate, short infection cycle and strong selection against foreign inserts. The hammerhead ribozyme (HHRz) is a small self-cleaving RNA molecule whose active residues have previously been identified by mutational...

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Detalles Bibliográficos
Autor principal: Olsthoorn, René CL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075628/
https://www.ncbi.nlm.nih.gov/pubmed/24946926
http://dx.doi.org/10.1186/1743-422X-11-116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075628/
https://www.ncbi.nlm.nih.gov/pubmed/24946926
http://dx.doi.org/10.1186/1743-422X-11-116

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