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Simulation of metabolism-based herb-drug interaction: towards safe and efficacious use of NIPRD-AM1

Objective: To evaluate the effect of NIPRD-AM1 on CYP3A4 in order to generate clinically significant data for its safe and efficacious use. Materials and Methods: NIPRD-AM1 is a phytomedicine developed from aqueous root extracts of Nauclea latifolia Smith (Rubiaceae) for the treatment of uncomplicat...

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Detalles Bibliográficos
Autores principales: Adzu, Bulus, Mustapha, Kudirat Bola, Masimirembwa, Collen, Obodozie, Obiageri, Kirim, Rukaiyatu Abdullahi, Gamaniel, Karniyus Shingu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075716/
https://www.ncbi.nlm.nih.gov/pubmed/25050275