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Highly efficient L-lactate production using engineered Escherichia coli with dissimilar temperature optima for L-lactate formation and cell growth

L-Lactic acid, one of the most important chiral molecules and organic acids, is produced via pyruvate from carbohydrates in diverse microorganisms catalyzed by an NAD(+)-dependent L-lactate dehydrogenase. Naturally, Escherichia coli does not produce L-lactate in noticeable amounts, but can cataboliz...

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Detalles Bibliográficos
Autores principales: Niu, Dandan, Tian, Kangming, Prior, Bernard A, Wang, Min, Wang, Zhengxiang, Lu, Fuping, Singh, Suren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075936/
https://www.ncbi.nlm.nih.gov/pubmed/24884499
http://dx.doi.org/10.1186/1475-2859-13-78