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Conformational Insights into the Lesion and Sequence Effects for Arylamine-Induced Translesion DNA Synthesis: (19)F NMR, Surface Plasmon Resonance, and Primer Kinetic Studies

[Image: see text] Adduct-induced DNA damage can affect transcription efficiency and DNA replication and repair. We previously investigated the effects of the 3′-next flanking base (G*CT vs G*CA; G*, FABP, N-(2′-deoxyguanosin-8-yl)-4′-fluoro-4-aminobiphenyl; FAF, N-(2′-deoxyguanosin-8-yl)-7-fluoro-2-...

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Detalles Bibliográficos
Autores principales: Jain, Vipin, Vaidyanathan, Vaidyanathan G., Patnaik, Satyakam, Gopal, Sathyaraj, Cho, Bongsup P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075988/
https://www.ncbi.nlm.nih.gov/pubmed/24915610
http://dx.doi.org/10.1021/bi5003212