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Conformational Insights into the Lesion and Sequence Effects for Arylamine-Induced Translesion DNA Synthesis: (19)F NMR, Surface Plasmon Resonance, and Primer Kinetic Studies
[Image: see text] Adduct-induced DNA damage can affect transcription efficiency and DNA replication and repair. We previously investigated the effects of the 3′-next flanking base (G*CT vs G*CA; G*, FABP, N-(2′-deoxyguanosin-8-yl)-4′-fluoro-4-aminobiphenyl; FAF, N-(2′-deoxyguanosin-8-yl)-7-fluoro-2-...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075988/ https://www.ncbi.nlm.nih.gov/pubmed/24915610 http://dx.doi.org/10.1021/bi5003212 |