Early Endosomal Escape of a Cyclic Cell-Penetrating Peptide Allows Effective Cytosolic Cargo Delivery

[Image: see text] Cyclic heptapeptide cyclo(FΦRRRRQ) (cFΦR(4), where Φ is l-2-naphthylalanine) was recently found to be efficiently internalized by mammalian cells. In this study, its mechanism of internalization was investigated by perturbing various endocytic events through the introduction of pha...

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Detalles Bibliográficos
Autores principales: Qian, Ziqing, LaRochelle, Jonathan R., Jiang, Bisheng, Lian, Wenlong, Hard, Ryan L., Selner, Nicholas G., Luechapanichkul, Rinrada, Barrios, Amy M., Pei, Dehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075989/
https://www.ncbi.nlm.nih.gov/pubmed/24896852
http://dx.doi.org/10.1021/bi5004102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075989/
https://www.ncbi.nlm.nih.gov/pubmed/24896852
http://dx.doi.org/10.1021/bi5004102

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