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Early Endosomal Escape of a Cyclic Cell-Penetrating Peptide Allows Effective Cytosolic Cargo Delivery
[Image: see text] Cyclic heptapeptide cyclo(FΦRRRRQ) (cFΦR(4), where Φ is l-2-naphthylalanine) was recently found to be efficiently internalized by mammalian cells. In this study, its mechanism of internalization was investigated by perturbing various endocytic events through the introduction of pha...
Autores principales: | Qian, Ziqing, LaRochelle, Jonathan R., Jiang, Bisheng, Lian, Wenlong, Hard, Ryan L., Selner, Nicholas G., Luechapanichkul, Rinrada, Barrios, Amy M., Pei, Dehua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075989/ https://www.ncbi.nlm.nih.gov/pubmed/24896852 http://dx.doi.org/10.1021/bi5004102 |
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