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Oncogenic MicroRNAs: miR-155, miR-19a, miR-181b, and miR-24 enable monitoring of early breast cancer in serum

BACKGROUND: MicroRNAs (miRs) represent a distinct class of posttranscriptional modulators of gene expression with remarkable stability in sera. Several miRs are oncogenic (oncomiRs) and are deregulated in the pathogenesis of breast cancer and function to inhibit tumor suppressors. Routine blood moni...

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Detalles Bibliográficos
Autores principales: Sochor, Marek, Basova, Petra, Pesta, Michal, Dusilkova, Nina, Bartos, Jiri, Burda, Pavel, Pospisil, Vit, Stopka, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075993/
https://www.ncbi.nlm.nih.gov/pubmed/24938880
http://dx.doi.org/10.1186/1471-2407-14-448