Ceramide kinase is required for a normal eicosanoid response and the subsequent orderly migration of fibroblasts

In these studies, the role of ceramide-1-phosphate (C1P) in the wound-healing process was investigated. Specifically, fibroblasts isolated from mice with the known anabolic enzyme for C1P, ceramide kinase (CERK), ablated (CERK(−/−) mice) and their wild-type littermates (CERK(+/+)) were subjected to...

Descripción completa

Detalles Bibliográficos
Autores principales: Wijesinghe, Dayanjan S., Brentnall, Matthew, Mietla, Jennifer A., Hoeferlin, L. Alexis, Diegelmann, Robert F., Boise, Lawrence H., Chalfant, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076082/
https://www.ncbi.nlm.nih.gov/pubmed/24823941
http://dx.doi.org/10.1194/jlr.M048207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076082/
https://www.ncbi.nlm.nih.gov/pubmed/24823941
http://dx.doi.org/10.1194/jlr.M048207

Ejemplares similares