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Ceramide kinase is required for a normal eicosanoid response and the subsequent orderly migration of fibroblasts
In these studies, the role of ceramide-1-phosphate (C1P) in the wound-healing process was investigated. Specifically, fibroblasts isolated from mice with the known anabolic enzyme for C1P, ceramide kinase (CERK), ablated (CERK(−/−) mice) and their wild-type littermates (CERK(+/+)) were subjected to...
Autores principales: | Wijesinghe, Dayanjan S., Brentnall, Matthew, Mietla, Jennifer A., Hoeferlin, L. Alexis, Diegelmann, Robert F., Boise, Lawrence H., Chalfant, Charles E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076082/ https://www.ncbi.nlm.nih.gov/pubmed/24823941 http://dx.doi.org/10.1194/jlr.M048207 |
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