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The Novel Role of HtrA1 in Gingivitis, Chronic and Aggressive Periodontitis

Proteolytic tissue degradation is a typical phenomenon in inflammatory periodontal diseases. HtrA1 (High temperature requirement A 1) has a serine protease activity and is able to degrade fibronectin whose fragments induce the expression and secretion of several matrix metalloproteinases (MMPs). The...

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Detalles Bibliográficos
Autores principales: Lorenzi, Teresa, Niţulescu, Elena Annabel, Zizzi, Antonio, Lorenzi, Maria, Paolinelli, Francesca, Aspriello, Simone Domenico, Baniţă, Monica, Crăiţoiu, Ştefania, Goteri, Gaia, Barbatelli, Giorgio, Lombardi, Tommaso, Di Felice, Roberto, Marzioni, Daniela, Rubini, Corrado, Castellucci, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076180/
https://www.ncbi.nlm.nih.gov/pubmed/24979214
http://dx.doi.org/10.1371/journal.pone.0096978