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In Vivo Efficacy of the Combination of Ciprofloxacin and Cefotaxime against Vibrio vulnificus Sepsis

OBJECTIVES: The in vivo efficacy of a cefotaxime-ciprofloxacin combination against Vibrio vulnificus and the effects on rtxA1 expression of commonly used antibiotics are unknown. METHODS: In vitro time-kill studies were performed to evaluate synergism. Female BALB/c mice were injected subcutaneously...

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Detalles Bibliográficos
Autores principales: Jang, Hee-Chang, Choi, Su-Mi, Kim, Hee Kyung, Kim, Sung-Eun, Kang, Seung-Ji, Park, Kyung-Hwa, Ryu, Phil Youl, Lee, Tae-Hoon, Kim, Young Ran, Rhee, Joon Haeng, Jung, Sook-In, Choy, Hyon E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076242/
https://www.ncbi.nlm.nih.gov/pubmed/24978586
http://dx.doi.org/10.1371/journal.pone.0101118