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Association between MTHFD1 G1958A Polymorphism and Neural Tube Defects Susceptibility: A Meta-Analysis

OBJECTIVES: The methylenetetrahydrofolate dehydrogenase (MTHFD1) gene, as one of the key genes involved in the folate pathway, has been reported to play a critical role in the pathogenesis of neural tube defects (NTDs). However, the results of published studies are contradictory and inconclusive. Th...

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Detalles Bibliográficos
Autores principales: Jiang, Jianxin, Zhang, Yanfei, Wei, Liang, Sun, Zhiyang, Liu, Zhongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076264/
https://www.ncbi.nlm.nih.gov/pubmed/24977710
http://dx.doi.org/10.1371/journal.pone.0101169