Phenotypic Characterization of miR-92a(−/−) Mice Reveals an Important Function of miR-92a in Skeletal Development

MicroRNAs (miRNAs, miRs) emerged as key regulators of gene expression. Germline hemizygous deletion of the gene that encodes the miR-17∼92 miRNA cluster was associated with microcephaly, short stature and digital abnormalities in humans. Mice deficient for the miR-17∼92 cluster phenocopy several fea...

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Detalles Bibliográficos
Autores principales: Penzkofer, Daniela, Bonauer, Angelika, Fischer, Ariane, Tups, Alexander, Brandes, Ralf P., Zeiher, Andreas M., Dimmeler, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076267/
https://www.ncbi.nlm.nih.gov/pubmed/24979655
http://dx.doi.org/10.1371/journal.pone.0101153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076267/
https://www.ncbi.nlm.nih.gov/pubmed/24979655
http://dx.doi.org/10.1371/journal.pone.0101153

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