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Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

[Image: see text] Albumin is the most abundant protein in human serum and drugs that are administered intravenously inevitably interact with it. We present here a series of platinum(IV) prodrugs designed specifically to enhance interaction with human serum albumin (HSA) for drug delivery. This goal...

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Detalles Bibliográficos
Autores principales: Zheng, Yao-Rong, Suntharalingam, Kogularamanan, Johnstone, Timothy C., Yoo, Hyunsuk, Lin, Wei, Brooks, Jamar G., Lippard, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076294/
https://www.ncbi.nlm.nih.gov/pubmed/24902769
http://dx.doi.org/10.1021/ja5038269