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Promoter hypermethylation of Wnt pathway inhibitors in hepatitis C virus - induced multistep hepatocarcinogenesis

BACKGROUND: Aberrant DNA methylation profiles are a characteristic feature of almost all types of cancers including hepatocellular carcinoma (HCC) and play an important role in carcinogenesis. In spite of the accumulating evidence that suggests appearance of such aberrations at precancerous stages,...

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Detalles Bibliográficos
Autores principales: Umer, Muhammad, Qureshi, Sohail Asif, Hashmi, Zahid Yasin, Raza, Asif, Ahmad, Janbaz, Rahman, Moazur, Iqbal, Mazhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076499/
https://www.ncbi.nlm.nih.gov/pubmed/24947038
http://dx.doi.org/10.1186/1743-422X-11-117