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Promoter hypermethylation of Wnt pathway inhibitors in hepatitis C virus - induced multistep hepatocarcinogenesis
BACKGROUND: Aberrant DNA methylation profiles are a characteristic feature of almost all types of cancers including hepatocellular carcinoma (HCC) and play an important role in carcinogenesis. In spite of the accumulating evidence that suggests appearance of such aberrations at precancerous stages,...
Autores principales: | Umer, Muhammad, Qureshi, Sohail Asif, Hashmi, Zahid Yasin, Raza, Asif, Ahmad, Janbaz, Rahman, Moazur, Iqbal, Mazhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076499/ https://www.ncbi.nlm.nih.gov/pubmed/24947038 http://dx.doi.org/10.1186/1743-422X-11-117 |
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