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Calcium-calmodulin does not alter the anion permeability of the mouse TMEM16A calcium-activated chloride channel

The transmembrane protein TMEM16A forms a Ca(2+)-activated Cl(−) channel that is permeable to many anions, including SCN(−), I(−), Br(−), Cl(−), and HCO(3)(−), and has been implicated in various physiological functions. Indeed, controlling anion permeation through the TMEM16A channel pore may be cri...

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Detalles Bibliográficos
Autores principales: Yu, Yawei, Kuan, Ai-Seon, Chen, Tsung-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076522/
https://www.ncbi.nlm.nih.gov/pubmed/24981232
http://dx.doi.org/10.1085/jgp.201411179