Determinants of ligand selectivity in a cyclic nucleotide–regulated potassium channel

Cyclic nucleotide–binding (CNB) domains regulate the activity of channels, kinases, exchange factors, and transcription factors. These proteins are highly variable in their ligand selectivity; some are highly selective for either cAMP or cGMP, whereas others are not. Several molecular determinants o...

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Detalles Bibliográficos
Autores principales: Pessoa, João, Fonseca, Fátima, Furini, Simone, Morais-Cabral, João H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076524/
https://www.ncbi.nlm.nih.gov/pubmed/24981229
http://dx.doi.org/10.1085/jgp.201311145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076524/
https://www.ncbi.nlm.nih.gov/pubmed/24981229
http://dx.doi.org/10.1085/jgp.201311145

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