Cargando…

The kinetics of ER fusion protein activation in vivo

Reversibly switchable proteins are powerful tools with which to explore protein function in vitro and in vivo. For example, the activity of many proteins fused to the hormone-binding domain of the modified estrogen receptor (ER(TAM)) can be regulated by provision or removal of 4-hydroxytamoxifen (4-...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilson, Catherine H., Gamper, Ivonne, Perfetto, Alessandra, Auw, Jeremy, Littlewood, Trevor D., Evan, Gerard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076531/
https://www.ncbi.nlm.nih.gov/pubmed/24662815
http://dx.doi.org/10.1038/onc.2014.78