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The kinetics of ER fusion protein activation in vivo
Reversibly switchable proteins are powerful tools with which to explore protein function in vitro and in vivo. For example, the activity of many proteins fused to the hormone-binding domain of the modified estrogen receptor (ER(TAM)) can be regulated by provision or removal of 4-hydroxytamoxifen (4-...
Autores principales: | Wilson, Catherine H., Gamper, Ivonne, Perfetto, Alessandra, Auw, Jeremy, Littlewood, Trevor D., Evan, Gerard I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076531/ https://www.ncbi.nlm.nih.gov/pubmed/24662815 http://dx.doi.org/10.1038/onc.2014.78 |
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