Cargando…
The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
Linear ubiquitination is a newly discovered posttranslational modification that is currently restricted to a small number of known protein substrates. The linear ubiquitination assembly complex (LUBAC), consisting of HOIL-1L, HOIP, and Sharpin, has been reported to activate NF-κB–mediated transcript...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076580/ https://www.ncbi.nlm.nih.gov/pubmed/24958845 http://dx.doi.org/10.1084/jem.20132486 |