A novel self-lipid antigen targets human T cells against CD1c(+) leukemias

T cells that recognize self-lipids presented by CD1c are frequent in the peripheral blood of healthy individuals and kill transformed hematopoietic cells, but little is known about their antigen specificity and potential antileukemia effects. We report that CD1c self-reactive T cells recognize a nov...

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Detalles Bibliográficos
Autores principales: Lepore, Marco, de Lalla, Claudia, Gundimeda, S. Ramanjaneyulu, Gsellinger, Heiko, Consonni, Michela, Garavaglia, Claudio, Sansano, Sebastiano, Piccolo, Francesco, Scelfo, Andrea, Häussinger, Daniel, Montagna, Daniela, Locatelli, Franco, Bonini, Chiara, Bondanza, Attilio, Forcina, Alessandra, Li, Zhiyuan, Ni, Guanghui, Ciceri, Fabio, Jenö, Paul, Xia, Chengfeng, Mori, Lucia, Dellabona, Paolo, Casorati, Giulia, De Libero, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076585/
https://www.ncbi.nlm.nih.gov/pubmed/24935257
http://dx.doi.org/10.1084/jem.20140410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076585/
https://www.ncbi.nlm.nih.gov/pubmed/24935257
http://dx.doi.org/10.1084/jem.20140410

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