Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell–derived IFN-γ

Paneth cells (PCs) are terminally differentiated, highly specialized secretory cells located at the base of the crypts of Lieberkühn in the small intestine. Besides their antimicrobial function, PCs serve as a component of the intestinal stem cell niche. By secreting granules containing bactericidal...

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Detalles Bibliográficos
Autores principales: Farin, Henner F., Karthaus, Wouter R., Kujala, Pekka, Rakhshandehroo, Maryam, Schwank, Gerald, Vries, Robert G.J., Kalkhoven, Eric, Nieuwenhuis, Edward E.S., Clevers, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076587/
https://www.ncbi.nlm.nih.gov/pubmed/24980747
http://dx.doi.org/10.1084/jem.20130753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076587/
https://www.ncbi.nlm.nih.gov/pubmed/24980747
http://dx.doi.org/10.1084/jem.20130753

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