Cargando…
Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell–derived IFN-γ
Paneth cells (PCs) are terminally differentiated, highly specialized secretory cells located at the base of the crypts of Lieberkühn in the small intestine. Besides their antimicrobial function, PCs serve as a component of the intestinal stem cell niche. By secreting granules containing bactericidal...
Autores principales: | Farin, Henner F., Karthaus, Wouter R., Kujala, Pekka, Rakhshandehroo, Maryam, Schwank, Gerald, Vries, Robert G.J., Kalkhoven, Eric, Nieuwenhuis, Edward E.S., Clevers, Hans |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076587/ https://www.ncbi.nlm.nih.gov/pubmed/24980747 http://dx.doi.org/10.1084/jem.20130753 |
Ejemplares similares
-
IFN-γ mediates Paneth cell death via suppression of mTOR
por: Araujo, Alessandra, et al.
Publicado: (2021) -
Parasite-induced T(H)1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells
por: Raetz, Megan, et al.
Publicado: (2012) -
miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine
por: Goga, Algera, et al.
Publicado: (2021) -
Paneth cells and necrotizing enterocolitis
por: Underwood, Mark A.
Publicado: (2012) -
PANETH CELL GRANULE OF MOUSE INTESTINE
por: Selzman, H. M., et al.
Publicado: (1962)