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Proteome-wide analysis of HIV-specific naive and memory CD4(+) T cells in unexposed blood donors

The preexisting HIV-1–specific T cell repertoire must influence both the immunodominance of T cells after infection and immunogenicity of vaccines. We directly compared two methods for measuring the preexisting CD4(+) T cell repertoire in healthy HIV-1–negative volunteers, the HLA-peptide tetramer e...

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Detalles Bibliográficos
Autores principales: Campion, Suzanne L., Brodie, Tess M., Fischer, William, Korber, Bette T., Rossetti, Astrea, Goonetilleke, Nilu, McMichael, Andrew J., Sallusto, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076590/
https://www.ncbi.nlm.nih.gov/pubmed/24958850
http://dx.doi.org/10.1084/jem.20130555