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Intergenerational genomic DNA methylation patterns in mouse hybrid strains

BACKGROUND: DNA methylation is a contributing factor to both rare and common human diseases, and plays a major role in development and gene silencing. While the variation of DNA methylation among individuals has been partially characterized, the degree to which methylation patterns are preserved acr...

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Detalles Bibliográficos
Autores principales: Orozco, Luz D, Rubbi, Liudmilla, Martin, Lisa J, Fang, Fang, Hormozdiari, Farhad, Che, Nam, Smith, Andrew D, Lusis, Aldons J, Pellegrini, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076608/
https://www.ncbi.nlm.nih.gov/pubmed/24887417
http://dx.doi.org/10.1186/gb-2014-15-5-r68