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The mechanistic target for rapamycin pathway is related to the phosphorylation score for estrogen receptor-α in human breast tumors in vivo

INTRODUCTION: A phosphorylation score for estrogen receptor-alpha (ERα), called P7 score, was shown previously to be an independent prognostic factor in breast cancer patients treated with tamoxifen. Since mechanistic target of rapamycin (mTOR) activation is implicated in resistance to endocrine the...

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Detalles Bibliográficos
Autores principales: Shrivastav, Anuraag, Bruce, Mary Christine, Jaksic, Danira, Bader, Tarek, Seekallu, Srinivas, Penner, Carla, Nugent, Zoann, Watson, Peter, Murphy, Leigh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076628/
https://www.ncbi.nlm.nih.gov/pubmed/24887419
http://dx.doi.org/10.1186/bcr3660