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The mechanistic target for rapamycin pathway is related to the phosphorylation score for estrogen receptor-α in human breast tumors in vivo
INTRODUCTION: A phosphorylation score for estrogen receptor-alpha (ERα), called P7 score, was shown previously to be an independent prognostic factor in breast cancer patients treated with tamoxifen. Since mechanistic target of rapamycin (mTOR) activation is implicated in resistance to endocrine the...
Autores principales: | Shrivastav, Anuraag, Bruce, Mary Christine, Jaksic, Danira, Bader, Tarek, Seekallu, Srinivas, Penner, Carla, Nugent, Zoann, Watson, Peter, Murphy, Leigh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076628/ https://www.ncbi.nlm.nih.gov/pubmed/24887419 http://dx.doi.org/10.1186/bcr3660 |
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