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Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors
INTRODUCTION: The molecular determinants of breast cancer resistance to first-line anthracycline-containing chemotherapy are unknown. METHODS: We examined the response to doxorubicin of organotypic cultures of primary human breast tumors ex vivo with respect to cell proliferation, DNA damage and mod...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076638/ https://www.ncbi.nlm.nih.gov/pubmed/24886669 http://dx.doi.org/10.1186/bcr3666 |