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Cyclin D1-CDK4 Controls Glucose Metabolism Independently of Cell Cycle Progression
Insulin constitutes a major evolutionarily conserved hormonal axis for maintaining glucose homeostasis(1-3); dysregulation of this axis causes diabetes(2,4). PGC-1α links insulin signaling to the expression of glucose and lipid metabolic genes(5-7). GCN5 acetylates PGC-1α and suppresses its transcri...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076706/ https://www.ncbi.nlm.nih.gov/pubmed/24870244 http://dx.doi.org/10.1038/nature13267 |