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Genetic analysis of dTSPO, an outer mitochondrial membrane protein, reveals its functions in apoptosis, longevity, and Aβ42-induced neurodegeneration

The outer mitochondrial membrane (OMM) protein, the translocator protein 18 kDa (TSPO), formerly named the peripheral benzodiazepine receptor (PBR), has been proposed to participate in the pathogenesis of neurodegenerative diseases. To clarify the TSPO function, we identified the Drosophila homolog,...

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Detalles Bibliográficos
Autores principales: Lin, Ran, Angelin, Alessia, Da Settimo, Federico, Martini, Claudia, Taliani, Sabrina, Zhu, Shigong, Wallace, Douglas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076708/
https://www.ncbi.nlm.nih.gov/pubmed/24977274
http://dx.doi.org/10.1111/acel.12200