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Genetic analysis of dTSPO, an outer mitochondrial membrane protein, reveals its functions in apoptosis, longevity, and Aβ42-induced neurodegeneration
The outer mitochondrial membrane (OMM) protein, the translocator protein 18 kDa (TSPO), formerly named the peripheral benzodiazepine receptor (PBR), has been proposed to participate in the pathogenesis of neurodegenerative diseases. To clarify the TSPO function, we identified the Drosophila homolog,...
Autores principales: | Lin, Ran, Angelin, Alessia, Da Settimo, Federico, Martini, Claudia, Taliani, Sabrina, Zhu, Shigong, Wallace, Douglas C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076708/ https://www.ncbi.nlm.nih.gov/pubmed/24977274 http://dx.doi.org/10.1111/acel.12200 |
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