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Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

Resistance of cancer cells to chemotherapy is a significant problem in oncology, and the development of sensitising agents or small-molecules with new mechanisms of action to kill these cells is needed. Autophagy is a cellular process responsible for the turnover of misfolded proteins or damaged org...

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Detalles Bibliográficos
Autores principales: Law, Betty Yuen Kwan, Chan, Wai Kit, Xu, Su Wei, Wang, Jing Rong, Bai, Li Ping, Liu, Liang, Wong, Vincent Kam Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076737/
https://www.ncbi.nlm.nih.gov/pubmed/24981420
http://dx.doi.org/10.1038/srep05510