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Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

Resistance of cancer cells to chemotherapy is a significant problem in oncology, and the development of sensitising agents or small-molecules with new mechanisms of action to kill these cells is needed. Autophagy is a cellular process responsible for the turnover of misfolded proteins or damaged org...

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Detalles Bibliográficos
Autores principales:	Law, Betty Yuen Kwan, Chan, Wai Kit, Xu, Su Wei, Wang, Jing Rong, Bai, Li Ping, Liu, Liang, Wong, Vincent Kam Wai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076737/ https://www.ncbi.nlm.nih.gov/pubmed/24981420 http://dx.doi.org/10.1038/srep05510

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