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Changes in Hippocampal Volume are Correlated with Cell Loss but Not with Seizure Frequency in Two Chronic Models of Temporal Lobe Epilepsy

Kainic acid (KA) or pilocarpine (PILO) have been used in rats to model human temporal lobe epilepsy (TLE) but the distribution and severity of structural lesions between these two models may differ. Magnetic resonance imaging (MRI) studies have used quantitative measurements of hippocampal T(2) (T(2...

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Detalles Bibliográficos
Autores principales: Polli, Roberson S., Malheiros, Jackeline M., dos Santos, Renan, Hamani, Clement, Longo, Beatriz M., Tannús, Alberto, Mello, Luiz E., Covolan, Luciene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076745/
https://www.ncbi.nlm.nih.gov/pubmed/25071699
http://dx.doi.org/10.3389/fneur.2014.00111