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Changes in Hippocampal Volume are Correlated with Cell Loss but Not with Seizure Frequency in Two Chronic Models of Temporal Lobe Epilepsy
Kainic acid (KA) or pilocarpine (PILO) have been used in rats to model human temporal lobe epilepsy (TLE) but the distribution and severity of structural lesions between these two models may differ. Magnetic resonance imaging (MRI) studies have used quantitative measurements of hippocampal T(2) (T(2...
Autores principales: | Polli, Roberson S., Malheiros, Jackeline M., dos Santos, Renan, Hamani, Clement, Longo, Beatriz M., Tannús, Alberto, Mello, Luiz E., Covolan, Luciene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076745/ https://www.ncbi.nlm.nih.gov/pubmed/25071699 http://dx.doi.org/10.3389/fneur.2014.00111 |
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