A Bayesian Perspective on Estimation of Variability and Uncertainty in Mechanism-Based Models

Mechanism-based pharmacokinetic/pharmacodynamic models have a fundamental basis in biology and pharmacology and, thus, are useful for hypothesis generation and extrapolation beyond the conditions of the original analysis data. The complexity of these models necessitates the incorporation of prior kn...

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Detalles Bibliográficos
Autor principal: Leil, T A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076806/
https://www.ncbi.nlm.nih.gov/pubmed/24964283
http://dx.doi.org/10.1038/psp.2014.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076806/
https://www.ncbi.nlm.nih.gov/pubmed/24964283
http://dx.doi.org/10.1038/psp.2014.19

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