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A Bayesian Perspective on Estimation of Variability and Uncertainty in Mechanism-Based Models
Mechanism-based pharmacokinetic/pharmacodynamic models have a fundamental basis in biology and pharmacology and, thus, are useful for hypothesis generation and extrapolation beyond the conditions of the original analysis data. The complexity of these models necessitates the incorporation of prior kn...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076806/ https://www.ncbi.nlm.nih.gov/pubmed/24964283 http://dx.doi.org/10.1038/psp.2014.19 |