TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens

BACKGROUND: Measuring the impact of combinations of genetic or chemical perturbations on cellular fitness, sometimes referred to as synthetic lethal screening, is a powerful method for obtaining novel insights into gene function and drug action. Especially when performed at large scales, gene-gene o...

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Detalles Bibliográficos
Autores principales: Muellner, Markus K, Duernberger, Gerhard, Ganglberger, Florian, Kerzendorfer, Claudia, Uras, Iris Z, Schoenegger, Andreas, Bagienski, Klaudia, Colinge, Jacques, Nijman, Sebastian MB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077039/
https://www.ncbi.nlm.nih.gov/pubmed/24712852
http://dx.doi.org/10.1186/1471-2105-15-98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077039/
https://www.ncbi.nlm.nih.gov/pubmed/24712852
http://dx.doi.org/10.1186/1471-2105-15-98

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